Donna L. Bratton, MD

Special Interests

Dr. Bratton’s clinical and research interests span the areas of cellular and molecular mechanisms in allergy, asthma, innate immunity, and inflammation. Her laboratory investigates endogenous signals for the resolution of inflammation, including lipid mediators and signals generated by dying inflammatory cells, with the goal of exploiting such signals therapeutically in inflammatory conditions.

Education

Education

1976 - 1980

Vanderbilt University Medical School (Nashville, TN), MD

Residency

1980 - 1983

Vanderbilt University (Nashville, TN), Intern and Resident: Pediatric

Fellowship

1984 - 1987

National Jewish Health for Immunology, Allergy/Immunology

1983 - 1984

Vanderbilt University (Nashville, TN), Neonatology

Board Certification

National Board Certification
Pediatric Board Certification - Written exam
Colorado Medical License
Pediatric Board Certification - Oral exam
Academy of Allergy/Immunology Board

Publications

Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Riches DWH, BrattonDL*, Sutherland ER*. Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol. Accepted 2012.

Frasch SC, Bratton DL. Emerging roles for lysophosphatidylserine in resolution of inflammation. Prog Lipid Res. 2012 Jul;51(3):199-207. Epub 2012 Mar 29. PMID: 22465125 [PubMed - in process] PMCID: PMC3365616 [Available on 2013/7/1]

Bratton DL, Henson PM. Neutrophil clearance: When the party’s over, cleanup begins. Trends Immunol. 32(8):350-7. Epub. Doi: 10,1016/j.it.2011.04.009. 2011.

Frasch SC, Fernandez-Boyanapalli RF, Berry KZ, Leslie CC, Bonventre JV, Murphy RC, Henson PM, Bratton DL. Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J Biol Chem. 286(14):12108-22, 2011. Epub 2011 Feb 4. PMID: 21297111

Fernandez-Boyanapalli R, Frasch SC, Riches DWH, Vandivier RW, Henson PM, Bratton DL. PPAR{gamma} activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease. Blood. Nov 25;116(22):4512-22, 2010 PMID: 20693431

Hospital Affiliations

• Children's Hospital Colorado

Academic Affiliations

Professor, University of Colorado Denver

Website Information

CgD

Bratton Lab