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SUNRISE Trial for Oral Steroid Dependent Asthma

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Trial Objectives

People with severe asthma are often dependent on oral corticosteroids, such as prednisone, to treat their condition. Researchers are currently investigating whether a new biologic treatment called tezepelumab may help to reduce or remove the need for these steroid medications.

In this study, tezepelumab will be compared against a treatment that does not contain any active medication, called a placebo. Either tezepelumab or the placebo will be given as an injection to study participants.

Who Can Participate

Adults ages 18-80 with a documented asthma diagnosis for at least 1 year requiring daily oral steroids for at least 6 months in addition to inhaled steroid treatments. Other criteria will be evaluated to see if you may participate in this study.

Age: 18-80 Gender Any

Estimated Time Commitment

14 visits over approximately 12 months. Most visits will last about 2 hours, but a few could take up to 4 hours.

Payment & Reimbursement

Payment Provided

Travel Reimbursement Not Available

Trial Contact

For more information, contact:

Allen Stevens

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Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors


Principal Investigators

Michael E. Wechsler

Michael E. Wechsler, MD, MMSc

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