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SEAL Study: Stopping Eczema and Allergy

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Trial Objectives

Researchers want to know if it is possible to prevent infants from developing allergic conditions, such as food allergies, by keeping their skin well hydrated and healthy through a national research study called SEAL. Participants will be split into two groups; one group will be given a moisturizer to be used on the infants’ skin with specific instructions, while the other group will not be given any special instructions or products to use. The children participating will be followed for three years to track whether or not the child develops allergies.

Who Can Participate

Infants with dry skin or atopic dermatitis (eczema).

Age: Newborn to 12-weeks-old Gender Any

Estimated Time Commitment

Three years, with six clinic visits and weekly or monthly phone calls with researchers

Payment & Reimbursement

Payment Provided

Travel Reimbursement Not Available

Trial Contact

For more information, contact:

Jane Rice


Susan Leung

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Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors

National Institutes of Health

Principal Investigators

Donald Y M Leung

Donald Y M Leung, PhD, MD


  • Mark Boguniewicz

    Mark Boguniewicz, MD

  • Jessica Hui (Beckman)

    Jessica Hui (Beckman), MD

  • Bruce J. Lanser

    Bruce J. Lanser, MD, MPH

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