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Improving the health of people with COPD

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Trial Objectives


Researchers want to know if an investigational medication can reduce the number of exacerbations in people with chronic obstructive pulmonary disease (COPD). They want to compare the effects, good or bad, of the investigational medication to a placebo (an inactive substance that looks the same and is administered the same as the investigational medication) on you and your COPD. In this study, participants will be given either Investigational medication or placebo (a substance that looks like the investigational medication, but has no active ingredients). They will take the assigned medication with their regular COPD medications. During clinic visits, participants will receive two injections, a blood draw, a physical exam, and a few other procedures depending on the visit.

Who Can Participate


Adults diagnosed with COPD by a physician, 12 months prior to screening and have a history of two or more moderate or severe exacerbations within a 12-month period.

Age: 40-90 Gender Any

Estimated Time Commitment


Clinic visits every two weeks up to 62 weeks. If eligible, participants may enter an extended treatment period for up to an additional 36 weeks.

Payment & Reimbursement


Payment Provided

Travel Reimbursement Not Available

Trial Contact


For more information, contact:

Maria Saucedo
303.398.1220

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Trial Location


National Jewish Main Campus, Denver, CO

Trial Sponsors


Genentech, Inc.

Principal Investigators

Russell P. Bowler

Russell P. Bowler, MD, PhD

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